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These information can be significantly informative and fascinating if the health results of e-cigarettes are compared directly with typical cigarettes or different tobacco products. Such comparisons will assist in identifying not solely e-cigarette–specific well being effects but also the consequences frequent to e-cigarettes and different tobacco products. Because cross-sectionals studies cannot set up directionality, progression, or causality, long-term longitudinal cohort research are wanted to assess how e-cigarette use affects the progression of subclinical disease. The outcomes of well-powered, multicenter, potential cohort research with significant follow-up will provide important knowledge for additional refining policy recommendations.
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